Pardes Habib

The paper uses a connectome model of the fruit-fly nervous system to simulate motor recovery after neuronal loss, finding that targeted cell replacement based on identity and connections improves recovery.

This paper develops CAR-NSC therapy targeting integrin αvβ3 to improve spatial distribution and tissue engagement of transplanted cells in stroke models.

The paper identifies and validates small-molecule inhibitors of TRMT2A that reduce polyQ aggregation and cell death in human cells.