Cancer BiologyCell stem cellPeer-reviewed
Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
Jin Young Lee, Nabora S. Reyes, Sang‐Ho Woo…·Tien Peng
This study identifies senescent fibroblasts in lung cancer stroma that alter tumor metabolism and plasticity, and shows that targeting these cells with XL888 reduces tumor burden.