Author

Nancy C. Allen

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jin Young LeeiD· 2 shared Nabora S. ReyesiD· 2 shared Ritusree Biswas· 2 shared Tien PengiD· 2 shared Vincent C. AuyeungiD· 2 shared Aaron Scott MansfieldiD· 1 shared Andrew J. LechneriD· 1 shared Ari B. MolofskyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Jin Young LeeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

Jin Young Lee, Nabora S. Reyes, Sang‐Ho Woo, Nancy C. Allen, Tsukasa Kadota, Andrew J. Lechner, Ritusree Biswas, Sakshi Goel, Fia Stratton, Chaoyuan Kuang, Tatsuya Tsukui, Vincent C. Auyeung, Aaron Scott Mansfield, Lindsay M. LaFave, Tien Peng

This study identifies senescent fibroblasts in lung cancer stroma that alter tumor metabolism and plasticity, and shows that targeting these cells with XL888 reduces tumor burden.

Cell stem cell · Nov 3, 2025Peer-reviewedCancer Biology

Fibroblast orchestration of inflammaging via NF-kB activation

Nancy C. Allen, Christian Ringler, Jin Young Lee, Nabora S. Reyes, Ritusree Biswas, Sofia E. Caryotakis, Mélia Magnen, Pedro Ruivo, Vincent C. Auyeung, Mark R. Looney, Averil I. Ma, Ari B. Molofsky, Tien Peng

This study shows that aged fibroblasts activate NF-kB, leading to immune changes like exhausted T cells, autoimmunity, and cancer, increasing susceptibility to age-related diseases.

bioRxiv · Oct 1, 2025 · PreprintImmunology