Author

Andrew J. Lechner

University of California, San FranciscoORCID 0009-0005-9729-4301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron Scott MansfieldiD· 1 shared Chaoyuan KuangiD· 1 shared Fia Stratton· 1 shared Jin Young LeeiD· 1 shared Lindsay M. LaFaveiD· 1 shared Nabora S. ReyesiD· 1 shared Nancy C. Allen· 1 shared Ritusree Biswas· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron Scott MansfieldORCID

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1 paper

Recent·Most cited

Cancer BiologyCell stem cellPeer-reviewedNov 3, 2025

Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

Jin Young Lee, Nabora S. Reyes, Sang‐Ho Woo…·Tien Peng

This study identifies senescent fibroblasts in lung cancer stroma that alter tumor metabolism and plasticity, and shows that targeting these cells with XL888 reduces tumor burden.

12 citations

mousehuman

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