Sylvain Trépout

Mind the Bend: Curved and Corrugated Cryo-Lamella for Improved Mechanical Resilience

This paper introduces curved and corrugated cryo-lamella designs to improve mechanical resilience and reduce lamella loss during electron microscopy sample preparation.

The IFT-A complex plays a major role in the assembly of anterograde intraflagellar transport trains

The paper investigates the role of IFT-A in anterograde intraflagellar transport in Trypanosoma brucei, finding that IFT140 is essential for train assembly.

About the alignment and 3D reconstruction of sparse cryo-scanning transmission electron tomography datasets

This paper analyzes fiducial alignment and reconstruction of sparse cryo-STET tilt-series, exploring the limits of sparse imaging for 3D reconstruction.

Mind the crack: Crack-arrest holes and soft-suspension support integration in cryo-lamella preparation for improved resistance to crack formation, fracture and deformation

This paper introduces two modifications to cryo-lamella preparation to reduce crack formation and improve mechanical resistance during imaging.

Mind the corner: Fillets in cryo-FIB lamella preparation to minimise sample loss caused by stress concentration and lamella breakage

The paper introduces a modification to cryo-FIB milling patterns by adding fillets to reduce stress concentration and lamella breakage, improving yield by 33%.

Accelerated plastic aging in suspension (APAS): A simple, reproducible approach for the generation of model micro- and nanoplastics through simulated environmental forces

The paper introduces APAS, a method to generate environmentally relevant micro- and nanoplastics by simulating natural aging processes, and shows its ability to produce complex particles with physicochemical properties similar to real-world MNPs.