Leelavathi Narayana Madhu

This study shows that extracellular vesicles from hiPSC-derived neural stem cells protect human neurons from Aβ-42 oligomer-induced neurodegeneration, mitochondrial dysfunction, and tau phosphorylation.

This study shows that intranasal hiPSC-NSC-EVs reduce neuroinflammaging in aged mice by modulating microglial transcriptome and signaling pathways.

This study examines the effects of short-term CSF1R inhibition in 5xFAD mice, showing reduced microglia, noninflammatory phenotype, and altered signaling pathways without affecting Aβ plaques.

This study shows that intranasally administered EVs from hiPSC-derived NSCs reduce microglial activation and improve brain function in an Alzheimer's model.