Author

Kalliopi Ziaka

University College LondonORCID 0000-0002-5853-2099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Michael E. CheethamiD· 4 shared Rosellina GuarascioiD· 3 shared Davide PiccoloiD· 2 shared Dimitra AthanasiouiD· 2 shared Kwan L. HauiD· 2 shared Rowan Asfahani· 2 shared Adriana Bakoulina· 1 shared Arto O. UrttiiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Michael E. CheethamORCID

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4 papers

Recent·Most cited

Lost in communication: How Mueller glia cells fail to maintain retinal integrity in USH1C retinal organoids

Nicole Wenck, Mark Zorin, Qiang Wang, Selina Kröll, Katharina Hay, Christof Rickert, María Méndez-Lago, Sivarajan Karunanithi, Dimitra Athanasiou, Kalliopi Ziaka, Pietro De Angeli, Katarína Štingl, Susanne Kohl, Michael E. Cheetham, Thomas Mittmann, Kerstin Nagel‐Wolfrum

This study uses retinal organoids from USH1C patients to show disrupted Muller glia signaling leads to retinal degeneration and loss of integrity.

bioRxiv · Jun 3, 2025 · PreprintCell Biology

Preventing light-induced toxicity in a new mouse model of rhodopsin sector retinitis pigmentosa

Rosellina Guarascio, Kalliopi Ziaka, Kwan L. Hau, Davide Piccolo, Sara Eliza Nieuwenhuis, Adriana Bakoulina, Rowan Asfahani, Mònica Aguilà, Dimitra Athanasiou, Diana Sefic Svara, Yumei Li, Rui Chen, Michael E. Cheetham

This study develops a mouse model of rhodopsin sector RP and shows that dim red light and S1PR agonist treatment can prevent light-induced photoreceptor degeneration.

bioRxiv · May 14, 2025 · PreprintNeuroscience

A proximity complementation assay to identify small molecules that enhance the traffic of ABCA4 misfolding variants.

Davide Piccolo, Christina Zarouchlioti, James Bellingham, Rosellina Guarascio, Kalliopi Ziaka, Robert S. Molday, Michael E. Cheetham

This study identifies small molecules that enhance ABCA4 misfolding variant trafficking to the plasma membrane using an in vitro platform.

International Journal of Molecular Sciences · Apr 20, 2024Peer-reviewedMolecular Biology

Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration

Blanca Arango‐González, Merve Sen, Rosellina Guarascio, Kalliopi Ziaka, Eva Maria del Amo, Kwan L. Hau, Hannah Poultney, Rowan Asfahani, Arto O. Urtti, Tsui‐Fen Chou, Sylvia Bolz, Raymond J. Deshaies, Wadood Haq, Michael E. Cheetham, Marius Ueffing

This study shows that inhibiting VCP activity rescues degenerating P23H rod cells and improves their function in retinal models of adRP.

bioRxiv · Nov 17, 2020 · PreprintNeuroscience