Roberto Frau

This study shows that prenatal THC exposure affects repetitive behavior and PFC neuronal excitability in male rats, with no change in dopamine transmission but altered gene expression and sex differences in Netrin-1.

This study shows sleep deprivation impairs information processing in the prefrontal cortex by disrupting chloride homeostasis through KCC2 reduction and BDNF-TrkB signaling, which can be mitigated by bumetanide or AP synthesis blockade.

This study investigates sex-specific effects of prenatal THC exposure on stress-induced dopamine dysfunction and sensorimotor gating in rats, showing a role for HPA axis and dopamine signaling.

This study shows that prenatal THC exposure does not alter mesolimbic dopamine function or behavior in female rats, unlike males.