Valeria Serra

This study investigates how prenatal cannabinoid exposure affects endocannabinoid-mediated synaptic plasticity in dopamine neurons, revealing a switch to nitric oxide signaling that alters excitatory and inhibitory plasticity.

This study shows that prenatal THC exposure affects repetitive behavior and PFC neuronal excitability in male rats, with no change in dopamine transmission but altered gene expression and sex differences in Netrin-1.

This study shows sleep deprivation impairs information processing in the prefrontal cortex by disrupting chloride homeostasis through KCC2 reduction and BDNF-TrkB signaling, which can be mitigated by bumetanide or AP synthesis blockade.

This study investigates sex-specific effects of prenatal THC exposure on stress-induced dopamine dysfunction and sensorimotor gating in rats, showing a role for HPA axis and dopamine signaling.

The paper shows that a gene-environment interaction involving MAO A gene variants and early life stress increases vulnerability to cocaine sensitization through endocannabinoid-dependent changes in GABAergic transmission in dopamine neurons.

This study shows that prenatal THC exposure does not alter mesolimbic dopamine function or behavior in female rats, unlike males.