Julien Capin

CF2H is a cell-free two-hybrid platform that rapidly detects high-affinity protein-protein interactions without cloning or purification.

This paper introduces a synthetic biology framework that enables tunable differentiation ratios in microbial consortia, validated in a mouse tumor model.

This paper introduces minireporters for monitoring gene expression and peptide production in cell-free systems, reducing DNA length and synthesis costs while maintaining reliable output.

The paper engineers ADDobody protein scaffolds to generate high-avidity ADDomer super-binders through genetic modification and structural validation.

This paper develops a baculovirus-based system for delivering large DNA cargoes for CRISPR-based genome editing in human cells, achieving up to 30% correct interventions.