Author

Ivana Semova

Boston Children's HospitalORCID 0000-0002-9754-1940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Briana R. DavisiD· 1 shared Cecelia KellyiD· 1 shared Colin R. LickwariD· 1 shared George Pengo· 1 shared Gilberto Padilla MercadoiD· 1 shared Goncalo Dias do ValeiD· 1 shared James M. DavisoniD· 1 shared Jeffrey G. McDonaldiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Briana R. DavisORCID

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Author profile →

2 papers

Recent·Most cited

The Diabetes Gene Tcf7l2 Organizes Gene Expression in the Liver and Regulates Amino Acid Metabolism

Joanna Krawczyk, William O’Connor, Pedro Henrique Vendramini, Mareike Schell, Kiran J. Biddinger, Matt Kanke, George Pengo, Ivana Semova, Tiffany Fougeray, Marcia C. Haigis, Krishna G. Aragam, Wouter H. Lamers, Linus T.-Y. Tsai, Praveen Sethupathy, Sudha B. Biddinger

This study shows Tcf7l2 maintains hepatic zonation and glutamine homeostasis, with loss of Tcf7l2 causing metabolic disruption and decreased glutamine levels.

Molecular Metabolism · Jul 16, 2025Peer-reviewedPhysiology

Transcriptional integration of distinct microbial and nutritional signals by the small intestinal epithelium

Colin R. Lickwar, James M. Davison, Cecelia Kelly, Gilberto Padilla Mercado, Jia Wen, Briana R. Davis, Matthew C. Tillman, Ivana Semova, Sarah F. Andres, Goncalo Dias do Vale, Jeffrey G. McDonald, John Franklin Rawls

This study investigates how the small intestinal epithelium integrates microbial and nutritional signals through transcriptional responses in mice, revealing distinct and overlapping regulatory mechanisms.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2022Peer-reviewedGenomics