Author

Evelyn Houtman

Leiden University Medical CenterORCID 0000-0002-6005-4583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Ingrid MeulenbeltiD· 2 shared Marcella van HoolwerffiD· 2 shared Y.F. RamosiD· 2 shared Enrike van der Linden· 1 shared Ghazaleh HajmousaiD· 1 shared Giorgia MazziniiD· 1 shared H. Eka D. SuchimaniD· 1 shared Hailiang MeiiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Ingrid MeulenbeltORCID

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2 papers

Recent·Most cited

Dynamic suspension culture enhances scalable maturation of hiPSC-derived cartilage organoids for regenerative medicine

Giorgia Mazzini, Evelyn Houtman, Marcella van Hoolwerff, Merel L. Janssen, Sayedeh Sana Sayedipour, Ghazaleh Hajmousa, Roxanne E. Kieltyka, Rachid Mahdad, Y.F. Ramos, Ingrid Meulenbelt

This paper develops a dynamic suspension culture system to improve the maturation of hiPSC-derived cartilage organoids, showing enhanced ECM deposition and gene expression compared to static culture.

bioRxiv · Jun 19, 2026 · PreprintCell Biology

RNA sequencing reveals interacting key determinants of osteoarthritis acting in subchondral bone and articular cartilage.

Margo Tuerlings, Marcella van Hoolwerff, Evelyn Houtman, H. Eka D. Suchiman, Nico Lakenberg, Hailiang Mei, Enrike van der Linden, Rob G. H. H. Nelissen, Y.F. Ramos, Rodrigo Coutinho de Almeida, Ingrid Meulenbelt

The paper identifies differentially expressed genes in OA subchondral bone and cartilage using RNA sequencing, highlighting IL11 and CHADL as potential druggable targets.

Arthritis & Rheumatology · Dec 1, 2020Peer-reviewedGenomics