Author

Natalia Rodrigo Melero

Barcelona Institute of Science and TechnologyORCID 0000-0002-6050-2446Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Organism:zebrafish· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Carlo CarolisiD· 2 shared Carlos Sánchez-Bolaños· 2 shared Julián CeróniD· 2 shared Miguel A. Moreno-MateosiD· 2 shared Alba Olaso Llorca· 1 shared Albert Bosch· 1 shared Alejandro RubioiD· 1 shared Alessandra GiorgettiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenetics

Carlo CarolisORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 16, 2026

A cold-adapted Cas9 nuclease from the deep ocean

Alba Olaso Llorca, Francesco Colizzi, Gerard Mingarro…·Julián Cerón

This paper characterizes DO1Cas9, a cold-adapted Cas9 nuclease from the deep ocean, showing improved activity under cold conditions and broader organismal applicability.

DOI 10.64898/2026.10.14.759226

C. eleganszebrafish

𝕏 PostBluesky

GeneticsNature CommunicationsPeer-reviewedMay 12, 2022

Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes

Jeremy Vicencio, Carlos Sánchez-Bolaños, Ismael Moreno-Sánchez…·Miguel A. Moreno-Mateos

This study demonstrates the use of SpG and SpRY CRISPR-Cas9 variants in zebrafish and C. elegans for genome editing, showing improved accessibility to previously uneditable sites.

48 citationstop 5%

zebrafishC. elegans

𝕏 PostBluesky