Greg J. Bashaw

This study identifies Commissureless as a substrate adapter for the Nedd4 E3 ubiquitin ligase, promoting axon growth across the midline by facilitating Robo1 ubiquitination and degradation.

This paper identifies a DCC variant causing mirror movement disorder and shows it disrupts the DCC-WAVE regulatory complex interaction, essential for Netrin-1 signaling.

This study identifies the WRC as a conserved effector of Robo signaling in axon repulsion across species.

This study compares midline repulsive signaling of Drosophila Robo1 and C. elegans SAX-3 using transgenic expression, showing SAX-3 can signal repulsion but less efficiently than Robo1.