Cheminformatic identification of small molecules targeting acute myeloid leukemia
Megan R. Daneman, Bernadetta Meika, Lois Armendariz, Elissa Tjahjono, Alexey V. Revtovich, Leonid A. Stolbov, Natthakan Thongon, Natalia Baran, Scott R. Gilbertson, Vladimir Poroikov, Natalia V. Kirienko
The paper identifies small molecules targeting AML by screening for compounds with predicted functions in apoptosis, glutathione metabolism, and autophagy, validating their efficacy in AML cells and patient-derived samples.
Leukemia · Aug 27, 2026Peer-reviewedCancer Biology