Author

Yuiko Takebayashi

University of BristolORCID 0000-0002-6224-0224Unclaimed ORCID profile · follow to get notified of new preprints

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Yuiko Takebayashi3 papers · University of Bristol;

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Catherine L. TookeiD· 2 shared JAMES M. SPENCERiD· 2 shared John M. ShawiD· 2 shared Adrian John MulhollandiD· 1 shared Andrew F. CadzowiD· 1 shared Carlos RedingiD· 1 shared Christopher John SchofieldiD· 1 shared Fergus HamiltoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Catherine L. TookeORCID

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2 papers

Recent·Most cited

BiochemistryRSC Medicinal ChemistryPeer-reviewedJan 1, 2025

Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases

Joseph F. Hoff, Kirsty E. Goudar, Karina Calvopiña…·JAMES M. SPENCER

This paper compares the potency of nacubactam and avibactam against OXA-48-like β-lactamases, finding that nacubactam is less potent due to electrostatic repulsion with Arg214.

5 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologyPLoS PathogensPeer-reviewedJun 6, 2024

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

Punyawee Dulyayangkul, Thomas Beavis, Winnie W. Y. Lee…·Matthew B. Avison

The paper shows that gene cassettes in an integron, amplified by IS26, confer resistance to amikacin and piperacillin/tazobactam, often leaving meropenem as the last-resort antibiotic.

6 citations

humanDNA methylation

𝕏 PostBluesky