High-Throughput Screening for Myelination Promoting Compounds Using Human Stem Cell-derived Oligodendrocyte Progenitor Cells Identifies Novel Targets
Weifeng Li, Cynthia A. Berlinicke, Yinyin Huang, Stefanie Giera, Anna G. McGrath, Weixiang Fang, Chaoran Chen, Felipe Takaesu, Xiaoli Chang, Yukan Duan, Dinesh Kumar, Calvin K.W. Chang, Hai‐Quan Mao, Guoqing Sheng, James C. Dodge, , Xitiz Chamling
The paper identifies novel pathways that enhance oligodendrocyte maturation and myelination through high-throughput screening of 2500 compounds using engineered human stem cell-derived OPCs.
iScience · Feb 8, 2023Peer-reviewedNeuroscience