Author

Yukan Duan

Johns Hopkins UniversityORCID 0000-0001-9614-8402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Cynthia A. BerlinickeiD· 3 shared Donald J. ZackiD· 3 shared Jie ChengiD· 2 shared Weifeng LiiD· 2 shared Anna G. McGrathiD· 1 shared Calvin K.W. ChangiD· 1 shared Casey J. KeuthaniD· 1 shared Chaoran CheniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Cynthia A. BerlinickeORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 28, 2026

Identification a Compact Promoter using a New Promoter Selection Strategy and Engineering Hybrid Pol II/III Enable Efficient Genome Editing in Human Retinal Ganglion Cells

Pingwu Zhang, Steven H. Zhang, Yen-Yu Chang…·Donald J. Zack

The paper identifies a compact Pol II promoter and hybrid Pol II/III promoters to enable efficient single-AAV delivery of SpCas9 for genome editing in human retinal ganglion cells.

1 citation

humanCRISPR screen

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NeuroscienceiSciencePeer-reviewedFeb 8, 2023

High-Throughput Screening for Myelination Promoting Compounds Using Human Stem Cell-derived Oligodendrocyte Progenitor Cells Identifies Novel Targets

Weifeng Li, Cynthia A. Berlinicke, Yinyin Huang…·Xitiz Chamling

The paper identifies novel pathways that enhance oligodendrocyte maturation and myelination through high-throughput screening of 2500 compounds using engineered human stem cell-derived OPCs.

19 citations

humanbulk RNA-seq

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GenomicsbioRxivPreprintFeb 13, 2018

Axon Guidance Signaling Modulates Epithelial to Mesenchymal Transition in Stem Cell-Derived Retinal Pigment Epithelium

Srinivas R. Sripathi, Melissa M. Liu, Ming-Wen Hu…·Donald J. Zack

This study investigates EMT in stem cell-derived RPE cells, identifying dysregulated axon guidance molecules during the process.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky