Author

Gunther Hollopeter

Cornell UniversityORCID 0000-0002-6409-0530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Approach:optimal transport· 1

Frequent Co-Authors

Gwendolyn M. BeachamiD· 3 shared Derek T. WeiiD· 2 shared Erika BeyrentiD· 2 shared Matthew J. PaszekiD· 2 shared Christopher A. AlabiiD· 1 shared Cyrus A HabasiD· 1 shared Dana N. Thornlow· 1 shared Jacky Lok Ka Kuo· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Gwendolyn M. BeachamORCID

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3 papers

Recent·Most cited

ASPPs multimerize protein phosphatase 1

Derek T Wei, Kayleigh N. Morrison, Gwendolyn M. Beacham, Erika Beyrent, Cyrus A Habas, Ying Zhang, Laurence A. Florens, Gunther Hollopeter

The paper shows ASPPs multimerize PP1 to form phosphatase hubs at cell-cell junctions, and mutant ASPPs disrupt this oligomerization, which can be rescued by forcing PP1 clustering.

PLoS Genetics · Oct 16, 2025Peer-reviewedCell Biology

Dimerization activates the Inversin complex in C. elegans

Erika Beyrent, Derek T. Wei, Gwendolyn M. Beacham, Sangwoo Park, Jian Zheng, Matthew J. Paszek, Gunther Hollopeter

The paper shows that dimerization activates the Inversin complex in C. elegans, with optogenetic stimulation and genetic studies supporting this mechanism.

Molecular Biology of the Cell · Aug 7, 2024Peer-reviewedCell Biology

Bio-orthogonal Glycan Imaging of Culture Cells and Whole Animal C. elegans with Expansion Microscopy

Joe Chin-Hun Kuo, Marshall J. Colville, Michelle R. Sorkin, Jacky Lok Ka Kuo, Ling Ting Huang, Dana N. Thornlow, Gwendolyn M. Beacham, Gunther Hollopeter, Matthew P. DeLisa, Christopher A. Alabi, Matthew J. Paszek

This paper develops multifunctional reagents for nanoscale imaging of glycans using expansion microscopy, validated in C. elegans and mammalian cells.

bioRxiv · Feb 1, 2024 · PreprintBioengineering