Gwendolyn M. Beacham

This study shows that stab2 is essential for fetal HSPC development in the niche, with loss of stab2 reducing HSPC numbers and altering sub-population balances.

The paper shows ASPPs multimerize PP1 to form phosphatase hubs at cell-cell junctions, and mutant ASPPs disrupt this oligomerization, which can be rescued by forcing PP1 clustering.

This paper develops multifunctional reagents for nanoscale imaging of glycans using expansion microscopy, validated in C. elegans and mammalian cells.

The paper shows that dimerization activates the Inversin complex in C. elegans, with optogenetic stimulation and genetic studies supporting this mechanism.