Author

Derek T Wei

Cornell UniversityORCID 0000-0001-6510-4458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Approach:optimal transport· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Erika BeyrentiD· 2 shared Gunther HollopeteriD· 2 shared Gwendolyn M. BeachamiD· 2 shared Cyrus A HabasiD· 1 shared Jian ZhengiD· 1 shared Kayleigh N. MorrisoniD· 1 shared Laurence A. FlorensiD· 1 shared Matthew J. PaszekiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Erika BeyrentORCID

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2 papers

Recent·Most cited

Cell BiologyPLoS GeneticsPeer-reviewedOct 16, 2025

ASPPs multimerize protein phosphatase 1

Derek T Wei, Kayleigh N. Morrison, Gwendolyn M. Beacham…·Gunther Hollopeter

The paper shows ASPPs multimerize PP1 to form phosphatase hubs at cell-cell junctions, and mutant ASPPs disrupt this oligomerization, which can be rescued by forcing PP1 clustering.

DOI 10.1371/journal.pgen.1011731

C. elegansexperimental assay

𝕏 PostBluesky

Cell BiologyMolecular Biology of the CellPeer-reviewedAug 7, 2024

Dimerization activates the Inversin complex in C. elegans

Erika Beyrent, Derek T. Wei, Gwendolyn M. Beacham…·Gunther Hollopeter

The paper shows that dimerization activates the Inversin complex in C. elegans, with optogenetic stimulation and genetic studies supporting this mechanism.

4 citations

C. elegansexperimental assay

𝕏 PostBluesky