Author

Kevin A. Strauss

Clinic for Special ChildrenORCID 0000-0002-6429-8657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:spatial transcriptomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alfred L. GeorgeiD· 1 shared Ali TorkamaniiD· 1 shared Allison Schreiber· 1 shared Annapurna PoduriiD· 1 shared Barbara CorneoiD· 1 shared Bianca MiglioriiD· 1 shared Bin XuiD· 1 shared Bryan Lynch· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Alfred L. GeorgeORCID

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Author profile →

3 papers

Recent·Most cited

Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

Michelle Dookwah, Shannon K. Wagner, Mayumi Ishihara, Seok‐Ho Yu, Heidi Ulrichs, Michael J. Kulik, Nadja Zeltner, Stephen Dalton, Kevin A. Strauss, Kazuhiro Aoki, Richard Steet, Michael Tiemeyer

This study investigates how two ST3GAL5 variants cause GM3SD by analyzing GSL biosynthesis and signaling changes in patient-derived iPSCs and NCCs.

Human Molecular Genetics · Sep 6, 2023Peer-reviewedNeuroscience

Cortical Overgrowth in a Preclinical Forebrain Organoid Model of CNTNAP2-Associated Autism Spectrum Disorder

Job O. de Jong, Ceyda Llapashtica, Matthieu Genestine, Kevin A. Strauss, Frank A. Provenzano, Yan Sun, Huixiang Zhu, Giuseppe P. Cortese, Francesco Gavino Brundu, Karlla Welch Brigatti, Barbara Corneo, Bianca Migliori, Raju Tomer, Steven A. Kushner, Christoph Kellendonk, , Sander Markx

This study uses patient-derived forebrain organoids to investigate the effects of a CNTNAP2 mutation on cortical development, finding increased cell proliferation and differential gene expression associated with ASD.

Nature Communications · Sep 1, 2021Peer-reviewedNeuroscience

High throughput Characterization of KCNB1 variants Associated with Developmental and Epileptic Encephalopathy

Seok Kyu Kang, Carlos G. Vanoye, Sunita N. Misra, Dennis M. Echevarria-Cooper, Jeffrey Dennis Calhoun, John B. O'Connor, Katarina L. Fabre, Dianalee McKnight, Laurie Demmer, Paula C. Goldenberg, Lauren E. Grote, Isabelle Thiffault, Carol Saunders, Kevin A. Strauss, Ali Torkamani, , Jennifer A. Kearney

This study evaluates 17 KCNB1 variants associated with DEE and NDD using high-throughput assays to identify functional defects in Kv2.1 channels.

Annals of Neurology · Oct 10, 2019Peer-reviewedGenetics