Author

Tomasz Nowikiewicz

Nicolaus Copernicus UniversityORCID 0000-0002-6492-4427Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anna KosteckaiD· 4 shared Arkadiusz PiotrowskiiD· 4 shared Łukasz SzylbergiD· 4 shared Ewa Śrutek· 3 shared Hanna DaviesiD· 3 shared Jakub MieczkowskiiD· 3 shared Jan Piotr DumanskiiD· 3 shared Katarzyna ChojnowskaiD· 3 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Anna KosteckaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 17, 2026

Spatial Transcriptomics of TNBC tumours and corresponding lymph node metastasis reveals immune hubs driven by TNF/NF-κB signalling of TMSB4X and CD74 expressing cells.

Adrian Perdyan, Urszula Ławrynowicz, Maciej Jaśkiewicz…·Jakub Mieczkowski

The paper uses spatial transcriptomics to identify immune hubs in TNBC lymph node metastases driven by TMSB4X and CD74, revealing spatially expanded inflammatory networks and myeloid-endothelial signaling.

DOI 10.64898/2026.03.15.711865

humanspatial transcriptomics

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Genetic & Genomic MedicinemedRxivPreprintOct 4, 2024

Beyond Tumors: Reduced survival linked to pathogenic PIK3CA and TP53 post-zygotic variants in the uninvolved breast tissue of recurrent cancer patients

Maria Andreou, Katarzyna Chojnowska, Natalia H. Filipowicz…·Arkadiusz Piotrowski

The paper identifies pathogenic post-zygotic variants in normal breast tissue of poor-prognosis cancer patients, linking them to reduced survival and disease recurrence.

DOI 10.1101/2024.10.04.24313634

humanwhole-exome sequencing

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GenomicsInternational Journal of CancerPeer-reviewedJun 8, 2024

Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes

Maria Andreou, Marcin Jąkalski, Katarzyna Duzowska…·Arkadiusz Piotrowski

4 citations

humanbulk RNA-seq

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Genetic & Genomic Medicinenpj Breast CancerPeer-reviewedJun 29, 2022

High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing.

Anna Kostecka, Tomasz Nowikiewicz, Paweł Olszewski…·Arkadiusz Piotrowski

27 citations

humanwhole-exome sequencing

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