Da‐Neng Wang

Structures of the human sodium-citrate cotransporter NaCT with and without substrates

This study determines the structures of the human NaCT protein in three states to elucidate the mechanism of sodium-substrate coupling in the DASS family.

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation

The paper identifies IMP-2380, a potent NorA inhibitor that enhances antibiotic activity by stabilizing the outward-open conformation of the efflux pump.

Using machine learning to predict quantitative phenotypes from protein and nucleic acid sequences

The paper uses machine learning to predict quantitative phenotypes like optimal growth temperature, pH, and oxygen tolerance from protein and nucleic acid sequences.

Prediction of Optimal Growth Temperature using only Genome Derived Features

This paper predicts the optimal growth temperature of prokaryotes using only genomic sequences with high accuracy.