A novel ciprofloxacin analogue enables daptomycin-mediated killing of resistant Staphylococcus aureus by increasing septum formation
Amber Y. Sefton, Elita Jauneikaite, Kam Pou Ha, Ravi Singh, Jacob D. Bradbury, Brigitte Lamy, Frederic J. Laurent, Edward W. Tate, Thomas Lanyon‐Hogg, Andrew M. Edwards
The paper shows that IMP-1700, a ciprofloxacin analogue, increases septum formation in S. aureus, enhancing daptomycin's effectiveness against resistant strains.
bioRxiv · Aug 24, 2026 · PreprintMicrobiology