Skyler L. Jackman

Mapping AMPA and NMDA receptors at mouse brain hippocampal synapses by cryo-ET

The paper maps AMPA and NMDA receptors at mouse hippocampal synapses using cryo-ET, revealing their distribution and relationship to glutamate release sites.

Mice with impaired synaptic facilitation exhibit deficits in cognitive flexibility

This study shows that mice lacking Synaptotagmin-7, which is required for synaptic facilitation, have impaired cognitive flexibility in dynamic reward tasks but not in stable ones.

Fast resupply of synaptic vesicles requires Synaptotagmin-3

This study identifies Synaptotagmin-3 as a high-affinity Ca2+ sensor that accelerates synaptic vesicle replenishment and short-term synaptic plasticity.

Synaptotagmin-7 enhances phasic dopamine release

This study shows that synaptotagmin-7 enhances phasic dopamine release in SNc neurons by mediating short-term facilitation during high-frequency firing.

Cerebellar Purkinje cell activity modulates aggressive behavior

This study shows that modulating cerebellar Purkinje cell activity in mice affects aggressive behavior without altering motor function.