Author

Lorenzo Bina

Erasmus MCORCID 0000-0002-6540-508XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Chris I. De ZeeuwiD· 3 shared Laurens W. J. BosmaniD· 3 shared Vincenzo RomanoiD· 2 shared Aaron D. GitleriD· 1 shared Aleksandar Arsović· 1 shared Antonio J. MirallesiD· 1 shared Camilla Ciapponi· 1 shared David MeierhoferiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Chris I. De ZeeuwORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ATXN2 polyglutamine expansion impairs QKI-dependent alternative splicing and oligodendrocyte maintenance

Nesli-Ece Şen, Jaime Eugenin von Bernhardi, Jubril Olamide Adeyemi, Aleksandar Arsović, Júlia Canet-Pons, Antonio J. Miralles, Jana Key, Lorenzo Bina, Vincenzo Romano, Meike Fellenz, Matthias Pietzke, Melanie Vanessa Halbach, Kay Seidel, Elif Fidan, Zeynep Ece Kaya Güleç, , Georg W. J. Auburger

This study shows that ATXN2 polyglutamine expansion impairs QKI-dependent alternative splicing and oligodendrocyte maintenance in a mouse model of SCA2.

bioRxiv · Aug 8, 2025 · PreprintNeuroscience

Cerebellar control of targeted tongue movements

Lorenzo Bina, Camilla Ciapponi, Siyang Yu, Xiang Wang, Laurens W. J. Bosman, Chris I. De Zeeuw

This study investigates how cerebellar Purkinje cells control tongue movements during drinking, showing that complex spikes signal target position changes and simple spikes influence movement direction.

The Journal of Physiology · Jan 26, 2025Peer-reviewedNeuroscience

Complex spike firing adapts to saliency of inputsand engages readiness to act

Lorenzo Bina, Vincenzo Romano, Tycho M. Hoogland, Laurens W. J. Bosman, Chris I. De Zeeuw

The paper investigates how climbing fiber activity in the cerebellum adapts to the saliency of sensory inputs and correlates with action readiness in mice during a go/no-go task.

Cell Reports · Dec 1, 2021Peer-reviewedNeuroscience