Cornelia M. Ulrich

Epigenetic Modulation, Intra-tumoral Microbiome and Immunity in Early Onset Colorectal Cancer

This study examines epigenetic, microbiome, and immune differences in early-onset colorectal cancer (EOCRC) compared to average-onset CRC, finding accelerated epigenetic aging and stronger immune-microbe correlations in EOCRC.

Candida albicans infiltrates colon and rectal cancers causing therapeutic resistance and decreased survival

This study identifies Candida albicans colonization in colorectal tumors as a factor linked to reduced survival and impaired radiation response.

Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction

The paper introduces pathway-based polygenic risk scores (pPRS) to detect gene-environment interactions, finding a significant interaction between NSAIDs and the TGF-β/GRHR pathway in colorectal cancer.

A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset

The paper introduces MEGA, a tool to identify cancer-associated microbes using RNA-seq data from the ORIEN dataset, leveraging graph attention networks and microbial community information.

Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis

This study uses Mendelian randomization to show that higher physical activity levels are associated with lower risks of breast and colorectal cancer.