Dunja Ferring–Appel

This study shows PKM2 binds RNA through a positively charged surface patch, with RNA binding influenced by its oligomeric state and allosteric regulator FBP.

This paper introduces soniCLIP, a CLIP-seq method that improves RNA target identification for RBPs by reducing input requirements and workflow complexity.

This study identifies MLP as a non-canonical RNA-binding protein in cardiomyocytes and shows its RNA-dependent interaction with cytoskeletal complexes.

The paper shows that specific cytosolic RNAs bind ATP5A1 precursor proteins and promote their mitochondrial import.

The paper characterizes RNA-binding protein landscapes in mouse organs using ex vivo eRIC, identifying over 1300 RBPs, many not previously found in cultured cells.

The paper shows RNA regulates ENO1 enzyme activity, affecting glycolysis and stem cell differentiation in human and mouse cells.