Author

Michelle Noble

European Molecular Biology LaboratoryORCID 0000-0002-1603-5887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aindrila ChatterjeeiD· 1 shared Alfredo CastellóiD· 1 shared Azman Embarc BuhiD· 1 shared Cátia IgrejaiD· 1 shared Chung-Te ChangiD· 1 shared David L. RobertsoniD· 1 shared Dunja Ferring–AppeliD· 1 shared Heike RampeltiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

Aindrila ChatterjeeORCID

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Author profile →

3 papers

Recent·Most cited

XRN1 supplies free nucleotides to feed alphavirus replication

Vincenzo Ruscica, Louisa Iselin, Ryan M. Hull, Azman Embarc Buh, Samyukta Narayanan, Natasha Palmalux, Namah Raut, Quan Gu, Honglin Chen, Marko Noerenberg, Zaydah R. de Laurent, Josmi Joseph, Michelle Noble, Cátia Igreja, David L. Robertson, , Alfredo Castelló

The paper shows that XRN1-mediated RNA decay provides nucleotides for alphavirus replication by recycling monophosphate nucleotides through the salvage pathway.

bioRxiv · Dec 9, 2024 · PreprintBiochemistry

Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions

Ting-Wen Chen, Hsiao‐Wei Liao, Michelle Noble, Jing-Yi Siao, Yu-Hsuan Cheng, Wei-Chung Chiang, Yi-Tzu Lo, Chung-Te Chang

This study investigates the role of human DCP1 paralogs in mRNA decapping and reveals their distinct gene regulatory functions through transcriptome and metabolome analyses.

eLife · Nov 1, 2024Peer-reviewedMolecular Biology

RNA promotes mitochondrial import of F1-ATP synthase subunit alpha (ATP5A1)

Aindrila Chatterjee, Michelle Noble, Thileepan Sekaran, Venkatraman Ravi, Dunja Ferring–Appel, Thomas Schwarzl, Heike Rampelt, Matthias W. Hentze

The paper shows that specific cytosolic RNAs bind ATP5A1 precursor proteins and promote their mitochondrial import.

bioRxiv · Aug 19, 2024 · PreprintCell Biology