Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity
Julia Su, Rohan V. Gupta, Scott van Hoof, Jakob Kreye, Harald Prüß, Benjamin P. Spielman, Lior Brimberg, Bruce T. Volpe, Patricio T. Huerta, Betty Diamond
The paper examines four new anti-Caspr2 antibodies, showing they target different epitopes and induce varying ASD-like phenotypes in male mice offspring.
Translational Psychiatry · Nov 15, 2025Peer-reviewedImmunology