Author

Lior Brimberg

Northwell HealthORCID 0000-0002-5262-3053Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Benjamin P. SpielmaniD· 2 shared Patricio T. HuertaiD· 2 shared Betty DiamondiD· 1 shared Bruce T. VolpeiD· 1 shared Christian Cruz· 1 shared Ciara Bagnall-MoreauiD· 1 shared Harald PrüßiD· 1 shared Jakob KreyeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Benjamin P. SpielmanORCID

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2 papers

Recent·Most cited

In Utero Exposure to Anti-Caspr2 Antibody Disrupts Parvalbumin Interneuron Function in the Hippocampus

Ciara Bagnall-Moreau, Joshua J. Strohl, Benjamin P. Spielman, Christian Cruz, Patricio T. Huerta, Lior Brimberg

This study shows that in utero exposure to anti-Caspr2 antibodies reduces PV+ interneurons and disrupts inhibitory circuitry in the hippocampus, linking it to ASD-related behavioral impairments.

Brain Behavior and Immunity · Nov 20, 2025Peer-reviewedNeuroscience

Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity

Julia Su, Rohan V. Gupta, Scott van Hoof, Jakob Kreye, Harald Prüß, Benjamin P. Spielman, Lior Brimberg, Bruce T. Volpe, Patricio T. Huerta, Betty Diamond

The paper examines four new anti-Caspr2 antibodies, showing they target different epitopes and induce varying ASD-like phenotypes in male mice offspring.

Translational Psychiatry · Nov 15, 2025Peer-reviewedImmunology