Author

Scott van Hoof

German Center for Neurodegenerative DiseasesORCID 0000-0002-2091-0904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Harald PrüßiD· 2 shared Jakob KreyeiD· 2 shared Adriana van CastereniD· 1 shared Angela Maria KaindliD· 1 shared Benjamin P. SpielmaniD· 1 shared Betty DiamondiD· 1 shared Bruce T. VolpeiD· 1 shared César Cordero Gómez· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Harald PrüßORCID

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2 papers

Recent·Most cited

Heterogeneity of anti-Caspr2 antibodies: specificity and pathogenicity

Julia Su, Rohan V. Gupta, Scott van Hoof, Jakob Kreye, Harald Prüß, Benjamin P. Spielman, Lior Brimberg, Bruce T. Volpe, Patricio T. Huerta, Betty Diamond

The paper examines four new anti-Caspr2 antibodies, showing they target different epitopes and induce varying ASD-like phenotypes in male mice offspring.

Translational Psychiatry · Nov 15, 2025Peer-reviewedImmunology

Encephalitis patient derived monoclonal GABAA receptor antibodies cause catatonia and epileptic seizures

Jakob Kreye, Sukhvir K. Wright, Adriana van Casteren, Laura Stöffler, Marie-Luise Machule, S. Momsen Reincke, Marc Nikolaus, Scott van Hoof, Elisa Sánchez-Sendín, Marie A. Homeyer, César Cordero Gómez, Hans‐Christian Kornau, Dietmar Schmitz, Angela Maria Kaindl, Philipp Boehm‐Sturm, , Harald Prüß

The paper demonstrates that patient-derived monoclonal GABAA receptor antibodies cause catatonia and seizures in rodents, providing a model for autoimmune encephalitis and supporting antibody depletion as a treatment.

DZNE Pub · Nov 1, 2021Peer-reviewedNeuroscience