Charles Vaughn Sindelar

Core-sheath coupling controls flagellar curvature and motility in Leptospira

This study reveals how core-sheath coupling in Leptospira flagella controls curvature and motility, showing its importance in viscous environments and infection.

Asymmetric architecture and adaptation of Treponema flagella

This study determines the asymmetric structure of Treponema denticola flagella and shows how it enables efficient motility.

High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory

This paper uses cryo-EM to solve high-resolution structures of actin-bound myo1c with and without ADP, revealing unique actin-binding orientation, ADP release pathway, and power stroke trajectory.

Structural Basis for the Clamping and Ca2+ Activation of SNARE-mediated Fusion by Synaptotagmin

This paper determines the structure of the Syt1-SNARE complex on lipid membranes using cryo-electron microscopy to elucidate how Syt1 clamps and activates SNARE-mediated fusion through Ca2+ and Mg2+ dependent interactions.