Mariano A. Aufiero

This study shows that ampicillin treatment impairs neutrophil-mediated immunity to Aspergillus fumigatus in mice, increasing mortality and fungal burden.

The paper identifies an IFN-STAT1-CYBB axis that mediates protective crosstalk between plasmacytoid dendritic cells and neutrophils during Aspergillus fumigatus infection.

This study identifies GM-CSF produced by SPC+ epithelial cells as critical for neutrophil-mediated immunity against Aspergillus fumigatus, enhancing fungal killing and host survival.

This study shows perforin-2 is not essential for antifungal immunity against A. fumigatus and C. albicans in immune-competent mice, emphasizing the need for co-housed littermate controls.