Author

Yuxun Zhang

University of PittsburghORCID 0000-0002-6682-012XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam C. Richert· 3 shared Eric S. GoetzmaniD· 3 shared Sivakama S. BharathiiD· 3 shared Birgit SchillingiD· 2 shared Bob B. ZhangiD· 2 shared Joanna BonsiD· 2 shared Abigail Hernandez· 1 shared Akira OdaiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiochemistry

Adam C. Richert

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Odd-chain dicarboxylic acid feeding recapitulates the biochemical phenotype of glutaric aciduria type-1 in mice

Adam C. Richert, Yuxun Zhang, Sivakama S. Bharathi, Abigail Hernandez, Tetyana Dodatko, Joanna Bons, Kayla E. Roundtree, Brandon B. Stauffer, Chunli Yu, Birgit Schilling, Sander M. Houten, Eric S. Goetzman

This study shows that feeding mice odd-chain dicarboxylic acids reproduces the biochemical features of glutaric aciduria type-1.

The FASEB Journal · Nov 6, 2025Peer-reviewedBiochemistry

Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders

Keaton J. Solo, Yuxun Zhang, Sivakama S. Bharathi, Bob B. Zhang, Adam C. Richert, Alexandra V. Schmidt, Shakuntala Basu, Clinton Van’t Land, Olivia D'Annibale, Timothy C. Wood, Jerry Vockley, Eric S. Goetzman

This study shows that oral octanoylcarnitine improves exercise tolerance and reduces metabolic stress in mouse models of long-chain fatty acid oxidation disorders.

JCI Insight · Oct 16, 2025Peer-reviewedBiochemistry

Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury

Takuto Chiba, Akira Oda, Yuxun Zhang, Katherine E. Pfister, Joanna Bons, Sivakama S. Bharathi, Ayako Kinoshita, Bob B. Zhang, Adam C. Richert, Birgit Schilling, Eric S. Goetzman, Sunder Sims‐Lucas

This study shows that loss of LCAD protects against acute kidney injury by reducing oxidative stress and enhancing peroxisomal fatty acid oxidation.

JCI Insight · Feb 11, 2025Peer-reviewedPathology