Author

Jin Hao

Broad InstituteORCID 0000-0002-6685-2017Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jin Hao1 paper · Stanford University

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Atsushi FukudaiD· 1 shared Bogdan BudnikiD· 1 shared Brian J. JosephiD· 1 shared Daniel A. MordesiD· 1 shared Feng TianiD· 1 shared Fengfeng BeiiD· 1 shared Francesco LimoneiD· 1 shared Gaby Cao· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Atsushi FukudaORCID

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2 papers

Recent·Most cited

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies

Qinglong Wang, Yiqi Wang, Yong‐hui Jiang, Ryan Donahue, Gaby Cao, Weixuan Yan, Hong Guo, Zhenghui Li, Jenna Liang, Jin Hao, Yi Lu, Fengfeng Bei, Qianbin Wang, Feng Tian

This study shows that OPTN dysfunction leads to neuroinflammation and RGC death in glaucoma, independent of IOP, and identifies OPTN-NPY signaling as a potential therapeutic target.

Communications Biology · Oct 16, 2025Peer-reviewedNeuroscience

Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons

Jin Hao, Michael F. Wells, Gengle Niu, Irune Guerra San Juan, Francesco Limone, Atsushi Fukuda, Marcel F. Leyton-Jaimes, Brian J. Joseph, Menglu Qian, Daniel A. Mordes, Bogdan Budnik, Zhixun Dou, Kevin C. Eggan

This study shows that TBK1 deficiency in human motor neurons causes TDP-43 proteinopathy through lysosomal dysfunction, and restoring TBK1 rescues the pathology.

bioRxiv · Oct 11, 2021 · PreprintNeuroscience