Murine gut microbiota dysbiosis via enteric infection modulates the foreign body response to a distal biomaterial implant
Brenda Yang, Natalie Rutkowski, Anna Ruta, Elise F. Gray-Gaillard, David R. Maestas, Sean H. Kelly, Kavita Krishnan, Xinqun Wu, Shaoguang Wu, Allen R. Chen, Connor D. Amelung, Joscelyn C. Mejías, Joshua S. T. Hooks, Isabel Vanderzee, Patricia Mensah, , Jennifer H. Elisseeff
This study shows that gut microbiota dysbiosis from enteric infection increases immune cell recruitment to a distant biomaterial implant, affecting the foreign body response.
Proceedings of the National Academy of Sciences · May 12, 2025Peer-reviewedBioengineering