Rinaldo Catta-Preta

The paper identifies differential oxygen levels as a driver of heterochrony in limb development between avian and mammalian embryos.

The paper introduces LS-MPRA and d-MPRA methods to map gene-specific regulatory regions at single nucleotide resolution, identifying known and novel CRMs in retinal and progenitor cells.

The paper identifies combinatorial TF-cRE interactions in mouse basal ganglia development, revealing modules that drive GABAergic neurogenesis and suppress other fates.

The paper identifies a transcription factor network and enhancers involved in cortical regional patterning using mouse embryonic data.

The paper shows POGZ promotes chromatin accessibility and expression of synaptic genes in mouse and human brains, and its reduction disrupts cortical function through interactions with ADNP.

This study examines transcriptional changes in rat hippocampus after traumatic brain injury, identifying time-dependent gene expression patterns and epigenetic modifications.

This study shows that deleting a non-canonical regulatory region of Scn1a in mice leads to reduced Scn1a expression and epileptic symptoms.

The paper uses scRNA-seq and enhancer-based labeling to map neuronal lineages in embryonic mouse basal ganglia and identifies novel lineage specification paths.

This study identifies CHD8 as a critical regulator of gene expression by analyzing transcriptomic and epigenomic data from multiple CHD8 knockdown and knockout models, revealing high-affinity interactions with genes involved in cellular homeostasis and neuronal function.