Franca Codazzi

Altered calcium responses and antioxidant properties in Friedreich's ataxia-like cerebellar astrocytes

This study investigates FXN depletion in cerebellar astrocytes, revealing altered calcium responses and antioxidant properties that may contribute to neurodegeneration in Friedreich's ataxia.

Two neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis.

This study characterizes two TDP-43 proteinopathy models in mouse neurons, revealing reduced axonal translation, increased oxidative stress, and presynaptic dysfunction linked to mRNA metabolism disruption.

A spatial-temporal map of glutamatergic neurogenesis in embryonic cerebellar nuclei uncovers a high degree of cellular heterogeneity

This study maps the spatial-temporal development of glutamatergic neurons in embryonic cerebellar nuclei, revealing significant cellular heterogeneity and distinct subpopulations.