Udayan M. Apte

Identification of co-expressed gene sets for major molecular initiating events in rodent liver carcinogenesis using wild type and knock out rats

The paper identifies co-expressed gene sets linked to molecular initiating events in rodent liver carcinogenesis by comparing wild-type and knockout rats exposed to chemical activators.

Multi-Omics after O-GlcNAc Alteration Identifies Cellular Processes Working Synergistically to Promote Aneuploidy

The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.

HNF4a regulates acyl chain remodeling and ether lipid accumulation in hepatic steatosis

This study identifies HNF4a's role in regulating acyl chain remodeling and ether lipid accumulation in hepatic steatosis through cold stress-induced changes in lipid metabolism.

IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

This study shows that Thm1 deletion in juvenile Pkd2 mice worsens biliary development and PLD, while adult Thm1 deletion has no effect, highlighting distinct roles of IFT-A and IFT-B in liver disease.