Author

Reza Nadafi

ORCID 0000-0002-6769-4145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Approach:microscopy & imaging analysis· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Rogier M. ReijmersiD· 2 shared Ailsa Greppi· 1 shared Alexia Katsarou· 1 shared Alice VitaliiD· 1 shared Anastasios KaradimitrisiD· 1 shared Anne C. RiosiD· 1 shared Aristeidis ChaidosiD· 1 shared Benjamin DraperiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Rogier M. ReijmersORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enhancing the iNKT cell immunotherapy platform by combining optimised CAR endodomains with novel iNKT engagers

Kanagaraju Ponnusamy, Klesti Karaxhuku, Yang Jiang, Lyra O. Randzavola, Hongwei Ren, Ilia Leontari, Bryan Lye, Mehmood Zaidi, Edward J Bartlett, Edward W. Tate, Vasileios Pardalis, Dimitrios Leonardos, Reza Nadafi, Irene Sarkar, Rogier M. Reijmers, , Anastasios Karadimitris

This study enhances iNKT cell immunotherapy by combining optimized CAR endodomains with novel iNKT-specific engagers to improve anti-myeloma activity.

bioRxiv · Oct 23, 2025 · PreprintImmunology

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

Marta Barisa, Henrike P. Muller, Elisa Zappa, Rivani Shah, Juliane L. Buhl, Benjamin Draper, Courtney Himsworth, Chantelle Bowers, Sophie Munnings-Tomes, Marilena Nicolaidou, Sonia Morlando, Kathleen Birley, Clara Leboreiro-Babe, Alice Vitali, Laura Privitera, , John Anderson

The paper evaluates how the functional avidity of anti-B7H3 CAR-T constructs relates to their ability to trigger effector function against tumors with varying antigen density.

Nature Communications · Aug 5, 2025Peer-reviewedBioengineering