Tim Czopka

This study compares oligodendrocyte recruitment in adaptive and regenerative myelination using zebrafish, showing distinct transcriptional programs and Gpr17-dependent pathways.

The paper shows that oligodendrocyte precursor cells (OPCs) use activity-dependent vesicular release to stabilize retinal ganglion cell pre-synapses in zebrafish.

This paper introduces CaBLAM, a bioluminescent Ca2+ indicator with improved dynamic range and Ca2+ affinity, enabling high-resolution imaging of cellular activity in cultured neurons and in vivo.

This study shows that mislocalisation of TDP-43 to the cytoplasm in neurons or oligodendrocytes causes axonopathy and dysmyelination, highlighting the role of cell-type-specific loss of function in neurodegeneration.

The paper identifies postsynaptic molecules in OPCs and shows their role in predicting myelin sheath formation through Ca2+ activity.

This study shows that oligodendrocyte precursor cells regulate axonal remodeling in the zebrafish visual system without forming myelin, affecting visual acuity.

The paper shows that clusters of Neurofascin A on axons predict node of Ranvier positions before myelination, independent of myelin sheath growth.

The paper identifies two functionally distinct subgroups of OPCs in zebrafish spinal cord, showing activity-dependent proliferation and differentiation.