Author

Xiaojiang Cui

Cedars-Sinai Medical CenterORCID 0000-0002-6843-736XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Armando E. GiulianoiD· 2 shared Andrew Martinez· 1 shared Bo WangiD· 1 shared Brianna Mulligan· 1 shared Edward RayiD· 1 shared Felipe Cortés‐LedesmaiD· 1 shared Florian Raths· 1 shared Hani GoodarziiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Armando E. GiulianoORCID

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2 papers

Recent·Most cited

TDP 2 modulates the expression of estrogen-responsive oncogenes

Nicholas Manguso, Minhyung Kim, Neeraj Joshi, Md Rasel Al Mahmud, Juan Aldaco, Ryusuke Suzuki, Felipe Cortés‐Ledesma, Xiaojiang Cui, Shintaro Yamada, Shunichi Takeda, Armando E. Giuliano, Sungyong You, Hisashi Tanaka

This study shows that TDP2 regulates estrogen-induced oncogene expression by resolving TOP2-induced DNA breaks, affecting MYC and CCND1 in ER-positive cells and mice.

NAR Cancer · Mar 15, 2024Peer-reviewedMolecular Biology

The molecular consequences of androgen activity in the human breast

Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, , Simon Knott

This study investigates the molecular effects of androgen in the human breast using single-cell transcriptome, chromatin, and spatial profiling of transgender men undergoing androgen therapy, revealing changes in gene expression, immune populations, vasculature, and metabolism.

Cell Genomics · Mar 1, 2023Peer-reviewedGenomics