Author

Fengxiang Tan

Guangzhou Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Mingzhu Wen· 2 shared Naihe JingiD· 2 shared Penglei Shen· 2 shared Rui SongiD· 2 shared Xianfa YangiD· 2 shared Yingying CheniD· 2 shared Zhen ShaoiD· 2 shared Bingbing Xie· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersDevelopmental Biology

Mingzhu Wen

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3 papers

Recent·Most cited

Spatiotemporal Regulatory Logics of Mouse Gastrulation

Xianfa Yang, Bingbing Xie, Penglei Shen, Yingying Chen, C.C. Li, Fengxiang Tan, Yumeng Yang, Yun Seok Yang, Rui Song, Panpan Mi, Zhiwen Liu, Mingzhu Wen, Patrick Tam, Shengbao Suo, Naihe Jing

This study constructs a spatiotemporal regulatory framework for mouse gastrulation using multi-omic data and reveals mechanisms of lineage commitment and symmetry breaking.

Nature Communications · Jan 12, 2026Peer-reviewedDevelopmental Biology

Gastrula-premarked posterior enhancer primes posterior tissue development through cross-talk with TGF-β signaling pathway

Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, , Xianfa Yang

The paper identifies a pre-marked enhancer, p-Enh, that primes posterior tissue development in mouse embryos through interaction with the TGF-β signaling pathway.

Advanced Science · Jun 29, 2025Peer-reviewedDevelopmental Biology

MAnorm2 for quantitatively comparing groups of ChIP-seq samples

Shiqi Tu, Mushan Li, Fengxiang Tan, Haojie Chen, Jian Xu, David J. Waxman, Yijing Zhang, Zhen Shao

MAnorm2 is a tool for comparing ChIP-seq samples across groups, improving differential binding detection by accounting for within-group variability and outperforming existing methods.

Genome Research · Jan 1, 2021Peer-reviewedBioinformatics