Erik Arne Richter

Site-resolved redox proteomics of human muscle after three exercise types shows modality-specific cysteine oxidation, and a p62 Cys113 switch tied to autophagy in myotubes and mitochondrial remodeling in mice.

This study shows that Rac1 deficiency in muscle reduces mitochondrial function and fatty acid metabolism, leading to muscle wasting and highlights potential therapeutic targets for age-related muscle decline.

The paper identifies an IL-6-associated SAA axis linked to muscle wasting and poor survival in cancer cachexia through plasma proteomics and functional studies.

The paper identifies a conserved postprandial metabolite, pTOS, that links nutrient intake to energy balance through a gut-brain pathway in pythons and mice, with potential relevance to humans.

The paper identifies proteomic and phosphoproteomic changes in skeletal muscle of lung cancer patients with cachexia, linking them to muscle wasting and signaling pathways.

This study shows that blocking ActRIIA/IIB increases muscle mass and strength in mice but causes glucose intolerance and reduced voluntary activity.

This study shows that Piezo2 in sensory neurons regulates brown and beige fat metabolism, preventing systemic hypermetabolism and improving insulin sensitivity.

This study identifies SLIRP as a mitochondrial mRNA stabilizing protein that regulates mitochondrial structure and respiration in skeletal muscle, with exercise improving mitochondrial function through increased mitoribosome capacity.

This study identifies Rac1 as a key regulator of exercise training adaptations by showing its role in protein synthesis, glycogen resynthesis, and running capacity in mice and human muscle.