Author

Michael Y. Ye

University of North Carolina at Chapel HillORCID 0000-0002-6884-6067Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Graham H. DieringiD· 3 shared Sean M. GayiD· 2 shared Andy Henrie· 1 shared Angie L. MordantiD· 1 shared Chih-Hsuan HsuiD· 1 shared Christine A. MillsiD· 1 shared Diane E. Youngstrom· 1 shared Elissavet ChartampilaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Graham H. DieringORCID

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3 papers

Recent·Most cited

Neurons and astrocytes have distinct organelle signatures and responses to stress

Shannon N. Rhoads, Weizhen Dong, Chih-Hsuan Hsu, Ngudiankama R. Mfulama, Ridhi Yarlagadda, Joey V. Ragusa, Michael Y. Ye, Andy Henrie, Maria Clara Zanellati, Graham H. Diering, Todd J. Cohen, Sarah Cohen

The paper characterizes organelle differences and stress responses between neurons and astrocytes using live-cell imaging and quantitative analysis.

Cell Reports · Sep 1, 2025Peer-reviewedCell Biology

Developing forebrain synapses are uniquely vulnerable to sleep loss

Sean M. Gay, Elissavet Chartampila, Julia Sparks Lord, Sawyer Grizzard, Tekla Maisashvili, Michael Y. Ye, Natalie K. Barker, Angie L. Mordant, Christine A. Mills, Laura E. Herring, Graham H. Diering

This study examines the effects of sleep deprivation on synaptic vulnerability across developmental stages in mice, finding heightened sensitivity in juveniles and links to ASD risk.

Proceedings of the National Academy of Sciences · Oct 23, 2024Peer-reviewedNeuroscience

Coordinated regulation of CB1 cannabinoid receptors and anandamide metabolism stabilizes network activity during homeostatic scaling down

Michael Y. Ye, Sarah Monroe, Sean M. Gay, Michael Armstrong, Diane E. Youngstrom, Fabio Urbina, Stephanie L. Gupton, Nichole A. Reisdorph, Graham H. Diering

This study shows that chronic hyperexcitation in cultured neurons triggers homeostatic downscaling and enhances endocannabinoid signaling through coordinated changes in FAAH, anandamide, and CB1.

eNeuro · Oct 31, 2022Peer-reviewedNeuroscience