The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir
Szu‐Wei Huang, Lorenzo Briganti, Arun S. Annamalai, Juliet Greenwood, Nikoloz Shkriabai, Reed Haney, Michael Armstrong, Michael F. Wempe, Satya Prakash Singh, Ashwanth Christopher Francis, Alan Engelman, Mamuka Kvaratskhelia
This study identifies the mechanism by which lenacapavir inhibits HIV-1 maturation by altering capsid protein assembly.
PLoS Pathogens · Jan 27, 2025Peer-reviewedMicrobiology