Matthew T. Aliota

Spondweni virus infection in pregnant rhesus macaques causes placental pathology without apparent fetal harm

This study infects pregnant rhesus macaques with Spondweni virus and finds placental pathology without fetal harm, contrasting with ZIKV-DAK-induced fetal demise.

Metagenomic surveillance of undiagnosed febrile illness in Nigeria does not reveal the etiological agent for most patients

The paper uses metagenomic sequencing to investigate undiagnosed febrile illness in Nigeria, identifying viruses and bacteria but finding no clear etiological agent for most cases.

Prenatal Zika Virus Exposure Disrupts Social-Emotional Development and Cortical Visual Function in Infant Macaques

This study shows that prenatal Zika virus exposure in macaques disrupts social-emotional development and visual function, independent of viral factors or maternal immunity.

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss In Rhesus Macaques

This study evaluates a Zika virus-like particle (VLP) vaccine in rhesus macaques, showing it reduces early pregnancy loss caused by a highly pathogenic ZIKV strain.

Zika virus-induced fetal demise is driven by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in Ifnar1-/- mice.

This study investigates how ZIKV strain and dose affect fetal demise in Ifnar1-/- mice by analyzing interferon responses in maternal-fetal tissues.

Wolbachia-mediated resistance to Zika virus infection in Aedes aegypti is dominated by diverse transcriptional regulation and weak evolutionary pressures

This study investigates Wolbachia's effect on ZIKV infection in Ae. aegypti using transcriptomics and viral sequencing, finding no clear transcriptional profile or evidence of ZIKV escape.

Using Barcoded Zika Virus to Assess virus Population Structure in vitro and in Aedes aegypti Mosquitoes

This study uses barcoded Zika virus to track genetic bottlenecks during transmission in vitro and in mosquitoes, showing stochasticity in viral dissemination.