Selective inhibition of respiratory complex I reveals a bioenergetic vulnerability in Francisella
Nimra Khalid, Chloe Marmarosh Van Horn, Danmeng Li, David A. Ostrov, Aria Eshraghi
This study identifies respiratory complex I as a selective vulnerability in Francisella and shows that tolfenpyrad inhibits it with species-specific antibacterial activity.
bioRxiv · Jun 5, 2026 · PreprintMicrobiology